If you can I'd try and stick to web-safe fonts. I've tried to muck around with @font-face and found it's implementation iffy at best between browsers, especially on Fisher Price Speak 'n Spells* - although admittedly this was a few years ago.
What I tend to do is use sIFR for headings as they can still be H1 tags for SEO, and then use a standard font for the main copy. Using different em sizing, line-heights and letter-spacings you can make old fonts look different and more interesting.
* I believe these are also called 'Macs'