Not with RadeonPro.
"Aside from a few dropped frames and a handful of spikes when the test changes scenes, our dual-Tahiti card enjoys much smoother sailing. In fact, the end result is often better than what you'd see from a single graphics card, with virtually no micro-stuttering left.
The RadeonPro software is more complicated to use than Nvidia's hardware-based solution because you have to manually create a new profile for each and every game. But the results speak for themselves. This is nothing short of a revelation for the folks who pin the scalability of their gaming machines on multi-GPU configurations, but hate the idea of micro-stuttering. John Mautari, the utility's developer, deserves big thanks from the crew at AMD, to be certain. "