Children who will be born knowing they will have serious, life-debilitating or low quality of life illnesses should be terminated regardless of the parents wishes.
To expand on this I was half watching a tv show on in the background the other day (maybe diy SOS or something like that?) and the parents said "oh yea we know this kid was going to be born brain damaged and require care for all his life but we had him anyway" and then they go on to show how the poor kid cant do anything except wave his hands back and forth (not even arms, just his wrists) sits there drooling as he cant close his mouth, has to be fed through a tube, has a ventilator, and so many meds hes probably somewhere in orbit being so high.
All I thought was how selfish of the parents to bring someone into the world like that.
If I ever was in that state I would rather be left to die.