Depends if you want computing power, efficiency, price or cool and quiet.
Supermicro X10SDV-6C+-TLN4F (
[email protected]) - £650
M393A4K40BB1-CRC (32GB ECC) x 4 - £800 (128GB)
For value its hard to out price a ryzen system but they are capped at 64GB ram where the above is designed for dozens of...