It really depends on the individual circumstances honestly, but you can certainly use values from others as a baseline. I am currently on PPT 210, TDC 150 and EDC 185. Majority of cores are set to -50, one is -25 as it kept throwing WHEA-Errors, whilst my best core is -10 and second best -15. As
@heartburnron mentioned reducing PPT does seem to correlate with reduced temps as well, but you will sacrifice elsewhere so it's all about finding the right balance for your set up.
PBO can be unreliable (I can pass benches, stress tests and play games without issue, but then I'll get an idle or low load WHEA-Error randomly), but it's also fun and addictive to play with.