MSI X99S SLI Plus Intel X99 (Socket 2011) DDR4 ATX Motherboard

X99S SLI Plus Intel X99 (Socket 2011) DDR4 ATX Motherboard

  • Socket 2011-3
  • Intel X99 Chipset
  • 4x PCI-E 3.0 x16
  • 2x PCI-E x1
  • 10x SATA 6Gb/s
  • SATA Express
  • M.2 Slot
  • 12x USB 3.0
  • 6x USB 2.0
  • Intel Gb LAN
  • 7.1 HD Audio
  • Quad Crossfire & Quad SLI Support
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Stock Code: MB-280-MS

EAN: 4719072361808

MPN: 7885-002R

Manufacturer: MSI

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Product information:

X99S SLI Plus Intel X99 (Socket 2011) DDR4 ATX Motherboard

Our X99S SLI PLUS comes in an all black design which is perfect for case-modders

  • An integrated Clock Generator supports more flexible BCLK adjustments, 100/125/167MHz, for reaching higher overclocking results
  • Solid and fast networking with Intel Gigabit LAN reaching speeds up to 1000 Mbps
  • Delivers stable 5V over all USB ports - Perfect for bitcoin mining and USB audio DACs
  • One-second overclocking through a single button for your convenience
  • Supports quad channel DDR4 memory up to 3333 MHz at low voltage up to 128GB
  • The best components for stability and performance in extreme conditions
  • Quad SLI™ & Quad CrossFire™ Support
  • 12x USB 3.0 & 10x SATA 6 Gb/s
  • SATA-Express on-board up to 10 Gb/s
  • New BIOS features such as Simple/Advanced mode, My Favorites, Hardware Monitor 2, Board Explorer and Memory Try It


GUARD-PRO protects the essential elements which increase stability in the worst conditions

Carefully selected materials, multiple PCB layers and shielding result in the best circuit protection for our motherboards. With MSI ECO Center you can physically cut the power to unused chips to save up to 19% power usage. All key components used in MSI motherboards have all passed military testing ensuring stable operation in the harshest environments. Each and every I/O port is protected against the hazards of Electro Static Discharge. With circuit protection, the MSI motherboard protects the CPU against overvolting and overheating. USB devices are protected from short circuiting too.

Turbo M.2

Turbo M.2 delivers next generation M.2 Gen3 x4 performance with transfer speeds 3 times as fast as conventional M.2 solutions

Turbo M.2 is the fastest onboard storage solution on the planet. MSI X99 motherboards allows Turbo M.2 (Gen3 x4) to be used at the same time as SATA-Express. All MSI X99 motherboards all come with M.2. Gen3 x4 which offers 32Gb/s, 3x the speed of standard M.2 (Gen2 x2). Combine this with a Samsung XP941 M.2 SSD and your system will reach the speed of light.

User-Friendly Software

Monitor everything with the user-friendly UI and manage the system with included software such as Live Update 6 and ECO Center

Command Center allows easy visual adjustment of system settings, automatically tune fans and gives complete freedom. It features an integrated unlimited RAMDisk too. Live Update 6 removes all the hassle of keeping your system up-to-date. It scans your PC and downloads the latest Drivers, BIOS and Firmware files straight to your system. ECO Power could also help users to manage their hardware to lower the power consumption.


CPU Support Supports New Intel® Core™ i7 Processor Extreme Edition for LGA2011-3 Socket
Chipset Intel® X99 Express Chipset
Memory Support Support eight DDR4 DIMMs 2133/2200(OC)/2400(OC)/2600(OC)/2666(OC)/2750(OC)/3000(OC)/3110(OC)/3333(OC) MHz, up to 128GB Max.
- Supports Quad-Channel mode
- Supports non-ECC, un-buffered memory
- Supports Intel® Extreme Memory Profile (XMP)
Slots 4 x PCIe 3.0 x16 slots, support up to 3-way mode
- 1-way mode: x16/ x0/ x0/ x0
- 2-way mode: x16/ x16/ x0/ x0*, 16/ x8/ x0/ x0**
- 3-way mode: x16/ x16/ x0/ x8*, x8/ x8/ x8/ x0**
* For the CPU that supports 40 PCIe lanes
** For the CPU that supports 28 PCIe lanes
On-Board SATA Intel® X99 Express Chipset
o 10 x SATA 6Gb/s ports (2x ports reserved for SATA Express port)*
- SATA1~6 support RAID 0, RAID 1, RAID 5 and RAID 10
- SATA7~10 ports only support IDE mode and AHCI mode.
- Supports Intel® Smart Response Technology (Windows 7/ 8/ 8.1)
o 1 x SATA Express port*
o 1 x M.2 port, supports up to 32Gb/s speed**
- M.2 port supports 4.2cm/ 6cm/ 8cm length module
- M.2 PCIe interface does not support RAID 0, RAID1, RAID 5 and RAID 10.
* The SATA Express port or SATA5~6 ports will be unavailable when installing the M.2 SATA interface module in the M.2 port.
** Intel RST does not support PCIe M.2 SSD with Legacy ROM.
USB o Intel X99 Express Chipset
- 6 x USB 3.0 ports (2 ports on the back panel, 4 ports available through the internal USB 3.0 connectors*)
- 6 x USB 2.0 ports (2 ports on the back panel, 4 ports available through the internal USB 2.0 connectors)
o ASMedia ASM1042AE
- 2 x USB 3.0 ports on the back panel
o VIA VL805
- 4 x USB 3.0 ports on the back panel
* Internal JUSB1 connector supports MSI Super Charger.
Audio Realtek® ALC892 Codec
- 7.1-Channel High Definition Audio
- Supports S/PDIF output
LAN 1 x Intel I218 Gigabit LAN
Wireless LAN N/A
Bluetooth N/A
Multi-GPU o Supports 3-Way NVIDIA® SLI™ Technology
o Supports 3-Way AMD® CrossFire™ Technology*
* Supports Windows 7 and Windows 8/ 8.1
Internal I/O Connectors - 1 x 24-pin AT x main power connector
- 1 x 8-pin AT x 12V power connector
- 10 x SATA 6Gb/s connectors
- 1 x SATA E xpress connector
- 1 x M.2 connector
- 2 x USB 2.0 connectors (supports additional 4 USB 2.0 ports)
- 2 x USB 3.0 connectors (supports additional 4 USB 3.0 ports)
- 2 x 4-pin CPU fan connectors
- 3 x 4-pin system fan connectors
- 1 x Front panel audio connector
- 2 x System panel connectors
- 1 x TPM module connector
- 1 x Chassis Intrusion connector
- 1 x Clear CMOS jumper
- 1 x Slow mode booting jumper
- 1 x Power button
- 1 x Reset button
- 1 x OC Genie button
- 1 x Multi-BIOS switch
Back Panel I/O Ports - 1 x PS/2 keyboard/ mouse combo port
- 2 x USB 2.0 ports
- 1 x Clear CMOS button
- 8 x USB 3.0 ports
- 1 x LAN (RJ45) port
- 1 x Optical S/PDIF OUT connector
- 5 x OFC audio jacks
Dimension 12 in. x 9.6 in. (30.5 cm x 24.4 cm) ATX Form Factor

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Customer review

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Average customer rating

(from 4 customer reviews)
All Time (4)

ok but could be better

Good board for the price (when it works), however the 16x SLI slots are to close together for good air cooling, which is odd, as its advertised as an SLI board?
Also I have had two now, both went back to MSI on an RMA due to stoppoing posting after a few weeks, MSI did send back a replacement board, but i moved to ASUS, which I do prefer.

So for non SLI, or SLI with non air cooling its a nice board for the price, howevber I had some bad experiences with quality, which was a shame


Excellent Board

I have overclocked my i7 5820k to 4.6 GHZ stable and it was a breeze as a noob overclocker. The bios is great for overclocking as it is so simple to the novice user. My only problem is i cant find the xmp profie for the ddr4 i purchase. Like i say im the noob overclocker so dont let this put you off. Excellent board and if you make a mistake it has the clear cmos button on the rear io to start agine 10/10 fom me


Great Motherboard for a Great Price

Although the cheap price and low end status compared to others it is a great board and have optimised my system greatly. I am using with a 5820K and Avexir 2400 ram both overclocked to 4.4Ghz and 3000Mhz respectively. No problems what so ever. The eco app is great for turning fans off and it comes with a lot of features. Looks sweet too. Good deal to get if you want reliable and cheap.

The only one issue is the PCIe slots being stupidly close. Still SLI works in the 1st and 4th slot nicely as the 1st and 3rd got my first card to 94Deg as it practically touches. Other than that great board!


All good

Bought this to accompany my 5930k, and whilst its taken me a while to get used to MSI's BIOS, I am now really enjoying using this board. Well built, well though out. Very stable, and overclocking well as well. It may be one of the cheaper X99 boards, but don't let that put you off. It's a fantastic board!


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